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Image Search Results
Journal: Journal of Alzheimer's disease : JAD
Article Title: Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice
doi: 10.3233/JAD-230089
Figure Lengend Snippet: Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Article Snippet: Activity data were analyzed by 2-way ANOVA using
Techniques: Activity Assay, Disruption
Journal: Journal of Alzheimer's disease : JAD
Article Title: Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice
doi: 10.3233/JAD-230089
Figure Lengend Snippet: Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Article Snippet: Activity data were analyzed by 2-way ANOVA using
Techniques: Activity Assay, Disruption