2-way anova (graphpad prism 10) Search Results


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GraphPad Software Inc 2-way anova (graphpad prism, version 10.0.2)
2 Way Anova (Graphpad Prism, Version 10.0.2), supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Graphpad Prism 10, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Prism 10, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
2way Anova, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Prism Version 7.00, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
Kruskal Wallis Test, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.
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Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.

Journal: Journal of Alzheimer's disease : JAD

Article Title: Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice

doi: 10.3233/JAD-230089

Figure Lengend Snippet: Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.

Article Snippet: Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10.

Techniques: Activity Assay, Disruption

Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.

Journal: Journal of Alzheimer's disease : JAD

Article Title: Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice

doi: 10.3233/JAD-230089

Figure Lengend Snippet: Diurnal locomotor activity levels in C57BL/6J and AβPP/PS1 mice under conditions of circadian disruption. A) Average locomotor activity during the lights on and lights off period in a 6-month and 12-month female C57BL/6J and AβPP/PS1 mice on either the ND or CD lighting schedule as measured via breakage of a cage-mounted infrared beam. B) 6-month and 12-month male C57BL/6J and AβPP/PS1 mice on either ND or CD lighting as measured via breakage of a cage-mounted infrared beam. C) IS of activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. D) IS of activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. E) Relative Amplitude of Activity for 6-month and 12-month female C57BL/6J and AβPP/PS1 mice. F) Relative Amplitude of Activity for 6-month and 12-month male C57BL/6J and AβPP/PS1 mice. G, H) Polar phasor plots of phase of mean peak activity on the angular axis (in 24-h time) and relative amplitude on the radial axis. Yellow box indicates time of lights off in the ND group. Blue box indicates time of lights off during days 1–5 in the CD group. Green vectors indicate AβPP/PS1 mice and red vectors indicate C57BL/6J mice. Black circles are C57BL/6J ND, black triangle are C57BL/6J CD, white circles are AβPP/PS1 ND, and white triangles are AβPP/PS1 CD. I) Time of activity onset in 6-month and 12-month female C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. J) Time of activity onset in 6-month and 12-month male C57BL/6J and AβPP/PS1 mice housed in CD lighting conditions. Data are represented as mean ± SEM. Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10. ∗p < 0.05; ∗∗p < 0.005; ∗∗∗p < 0.0005.

Article Snippet: Activity data were analyzed by 2-way ANOVA using GraphPad Prism 10.

Techniques: Activity Assay, Disruption